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Alternative approaches : Consideration of whether optimizing tirzepatide dosing, lifestyle interventions, or other evidence-based therapies might achieve goals without off-label combination therapy

The rationale for these modifications is rooted in a practical challenge: tetrapeptides like Epithalon are rapidly degraded by aminopeptidases and carboxypeptidases in experimental systems, limiting the duration of exposure in research protocols

This condition remains untreated, yet it significantly influences cognitive decline and stroke incidence among older individuals

D., Trubiani, O., Pizzicannella, J., & Diomede, F